HCA Healthcare Research Institute
HCA Healthcare Research Institute is the multispecialty clinical research arm of HCA Healthcare. Our expert physicians work with trusted pharmaceutical and biotechnology partners to unlock insights from real-world data and conduct clinical studies leading to breakthroughs in science, medicine and care for all people.
The HCA Healthcare Research Institute is charting a bold new course—shaping the future of clinical research.
We're expanding access to innovative therapies, accelerating discovery and transforming patient care across the nation -- powered by passion, expertise and an unwavering commitment to advancing health.
Today's research paves the way for tomorrow's breakthroughs. By leveraging real-world data and transforming groundbreaking ideas into life-changing care, we are working through every discovery to create a healthy, more hopeful future for our patients and communities.
Who we are
How we do it
What we offer
- 54Sites in the network and growing
- 523Total active studies
- 230National experienced principal investigators
- 14Specialties
*Data as of December 31, 2025
HCA Healthcare Research Institute
Our network
HCA Healthcare Research Institute’s site network connects sponsors and contract research organizations with national scientific key opinion leaders and community-based hospitals across the country. We perform research in a variety of therapeutic areas, including oncology, cardiology, neuroscience, pulmonary and thoracic, and inpatient surgical/device trials, collaborating across physician groups to help improve patient access and maximize start-up efficiency.
Our patients
When you participate in a clinical research trial, you contribute to unlocking breakthroughs in science and the future of healthcare. Many medications and treatments would not exist without research participants. People of all ages and backgrounds can participate in clinical trials. Talk to your doctor to learn more about participating in a clinical trial and contributing to the future of medicine.
Our partners
HCA Healthcare is a leader in research. Our approximately 44 million annual patient encounters provide a wealth of data that is utilized for records-based initiatives.
The Research Institute serves as a valuable partner and liaison between research study sponsors and our network of sites in communities across the country.
The Research Institute offers:
- A single point of contact to streamline trials and site activation
- Multi-specialty centralized support services
- Access to diverse, quality sites with proven performance
- Experienced principal investigator support across a network of therapeutic areas
Our physicians
As part of a learning health system, we are unlocking insights into real-world data and clinical studies that lead to scientific breakthroughs and transform patient care.
Join a growing network of more than 200 principal investigators participating in local and national research initiatives, advancing care for our patients.
We believe in doing what is right for our patients and colleagues and take great pride in being a positive influence in the many communities we serve.
Sam Hazen
Chief Executive Officer
Advancing patient care to improve more lives
The HCA Healthcare Research Institute helps shape the future of patient care industrywide, bringing breakthroughs in science and medicine to our patients in their community.
The HCA Healthcare Research Institute helps shape the future of patient care industrywide, bringing breakthroughs in science and medicine to our patients in their community.
"Clinical research is the cornerstone of modern healthcare fueling innovation, advancing treatments, and transforming lives. At HCA Healthcare’s Research Institute, we are pioneering new treatments to enhance existing therapeutic approaches, the significance of clinical research cannot be overstated. It is fundamental to our mission at HCA where above all else, we are committed to the care and improvement of human life."
Dr. Greg Fontana
National Director Cardiothoracic Surgery
Innovative care close to home
With 50 sites across eleven states, the Research Institute’s capacity and capabilities continue to strengthen across the enterprise. Our programs support nine specialties – Cardiac and Vascular, Oncology, Infectious Disease, Pulmonary and Thoracic, Women and Children’s, Neuroscience, Musculoskeletal, Robotics and Behavioral Health.
Capital
Catholic Medical Center
- Cardiac and Vascular
CJW Medical Center
- Cardiac and Vascular, Oncology, Infectious Disease, Neuroscience
Henrico Doctor’s Hospital
- Cardiac and Vascular, Oncology
Continental
HCA HealthONE Aurora
- Cardiac and Vascular
HCA HealthONE Presbyterian St. Luke’s
- Musculoskeletal
HCA HealthONE Rose
- Musculoskeletal
HCA HealthONE Sky Ridge
- Musculoskeletal
HCA HealthONE Swedish
- Neuroscience, Musculoskeletal
East Florida
HCA Florida JFK Hospital
- Cardiac and Vascular, Neuroscience, Oncology, Musculoskeletal
HCA Florida Mercy Hospital
- Bariatrics, Cardiac and Vascular, Oncology, Robotics
Far West
Los Robles Regional Medical Center
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
MountainView Hospital
- Robotics
Riverside Community Hospital
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
Gulf Coast
Corpus Christi Medical Center
- Cardiac and Vascular
HCA Houston Healthcare Clear Lake
- Infectious Disease, Pulmonary & Thoracic, Robotics
HCA Houston Healthcare Kingwood
- Infectious Disease, Neuroscience
HCA Houston Healthcare Medical Center
- Cardiac and Vascular
HCA Houston Healthcare North Cypress
- Neuroscience, Oncology
Rio Grande Regional Hospital
- Women and Children's
The Woman’s Hospital of Texas
- Women and Children's
MidAmerica
Centerpoint Medical Center
- Oncology
Menorah Medical Center
- Oncology
Research Medical Center
- Oncology
Mountain
St. Mark’s Hospital
- Cardiac and Vascular
North Carolina
Mission Hospital
- Cardiac and Vascular, Oncology, Neuroscience, Pulmonary and Thoracic
North Florida
HCA Florida Ocala Hospital
- Cardiac and Vascular, Neuroscience
HCA Florida Osceola Hospital
- Cardiac and Vascular
North Texas
Medical City Arlington
- Cardiac and Vascular
Medical City Dallas
- Cardiac and Vascular, Infectious Disease, Musculoskeletal, Pulmonary and Thoracic, Women and Children's
Medical City Fort Worth
- Infectious Disease, Pulmonary & Thoracic
Medical City Heart Hospital
- Infectious Disease
Medical City Plano
- Cardiac and Vascular, Infectious Disease, Musculoskeletal, Neuroscience, Pulmonary & Thoracic
Medical City Spine Hospital
- Infectious Disease
San Antonio
Methodist Children's Hospital
- Oncology
Methodist Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic, Robotics, Solid Organ Transplant, Women and Children's
Methodist Hospital Metropolitan
- Infectious Disease, Pulmonary & Thoracic
Methodist Hospital Specialty and Transplant
- Solid Organ Transplant
Methodist Hospital Stone Oak
- Cardiac and Vascular, Infectious Disease, Neuroscience
Methodist Hospital Texsan
- Cardiac and Vascular
South Atlantic
Doctors Hospital of Augusta
- Burn Care
Grand Strand Medical Center
- Cardiac and Vascular
HCA Florida Memorial Hospital
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
Memorial Savannah
- Cardiac and Vascular, Oncology, Women & Children’s
Trident Medical Center
- Cardiac and Vascular, Oncology
TriStar
TriStar Centennial Medical Center
- Cardiac and Vascular, Oncology, Infectious Disease, Neuroscience, Pulmonary and Thoracic, Robotics
TriStar Skyline Medical Center
- Neuroscience
West Florida
HCA Florida Brandon Hospital
- Cardiac and Vascular, Infectious Disease
HCA Florida Fawcett Hospital
- Cardiac and Vascular
HCA Florida Largo Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic
HCA Florida Northside Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic
HCA Florida Trinity Hospital
- Infectious Disease
HCA Florida West Tampa
- Oncology
Catholic Medical Center
- Cardiac and Vascular
CJW Medical Center
- Cardiac and Vascular, Oncology, Infectious Disease, Neuroscience
Henrico Doctor’s Hospital
- Cardiac and Vascular, Oncology
HCA HealthONE Aurora
- Cardiac and Vascular
HCA HealthONE Presbyterian St. Luke’s
- Musculoskeletal
HCA HealthONE Rose
- Musculoskeletal
HCA HealthONE Sky Ridge
- Musculoskeletal
HCA HealthONE Swedish
- Neuroscience, Musculoskeletal
HCA Florida JFK Hospital
- Cardiac and Vascular, Neuroscience, Oncology, Musculoskeletal
HCA Florida Mercy Hospital
- Bariatrics, Cardiac and Vascular, Oncology, Robotics
Los Robles Regional Medical Center
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
MountainView Hospital
- Robotics
Riverside Community Hospital
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
Corpus Christi Medical Center
- Cardiac and Vascular
HCA Houston Healthcare Clear Lake
- Infectious Disease, Pulmonary & Thoracic, Robotics
HCA Houston Healthcare Kingwood
- Infectious Disease, Neuroscience
HCA Houston Healthcare Medical Center
- Cardiac and Vascular
HCA Houston Healthcare North Cypress
- Neuroscience, Oncology
Rio Grande Regional Hospital
- Women and Children's
The Woman’s Hospital of Texas
- Women and Children's
Centerpoint Medical Center
- Oncology
Menorah Medical Center
- Oncology
Research Medical Center
- Oncology
St. Mark’s Hospital
- Cardiac and Vascular
Mission Hospital
- Cardiac and Vascular, Oncology, Neuroscience, Pulmonary and Thoracic
HCA Florida Ocala Hospital
- Cardiac and Vascular, Neuroscience
HCA Florida Osceola Hospital
- Cardiac and Vascular
Medical City Arlington
- Cardiac and Vascular
Medical City Dallas
- Cardiac and Vascular, Infectious Disease, Musculoskeletal, Pulmonary and Thoracic, Women and Children's
Medical City Fort Worth
- Infectious Disease, Pulmonary & Thoracic
Medical City Heart Hospital
- Infectious Disease
Medical City Plano
- Cardiac and Vascular, Infectious Disease, Musculoskeletal, Neuroscience, Pulmonary & Thoracic
Medical City Spine Hospital
- Infectious Disease
Methodist Children's Hospital
- Oncology
Methodist Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic, Robotics, Solid Organ Transplant, Women and Children's
Methodist Hospital Metropolitan
- Infectious Disease, Pulmonary & Thoracic
Methodist Hospital Specialty and Transplant
- Solid Organ Transplant
Methodist Hospital Stone Oak
- Cardiac and Vascular, Infectious Disease, Neuroscience
Methodist Hospital Texsan
- Cardiac and Vascular
Doctors Hospital of Augusta
- Burn Care
Grand Strand Medical Center
- Cardiac and Vascular
HCA Florida Memorial Hospital
- Cardiac and Vascular, Neuroscience, Pulmonary and Thoracic
Memorial Savannah
- Cardiac and Vascular, Oncology, Women & Children’s
Trident Medical Center
- Cardiac and Vascular, Oncology
TriStar Centennial Medical Center
- Cardiac and Vascular, Oncology, Infectious Disease, Neuroscience, Pulmonary and Thoracic, Robotics
TriStar Skyline Medical Center
- Neuroscience
HCA Florida Brandon Hospital
- Cardiac and Vascular, Infectious Disease
HCA Florida Fawcett Hospital
- Cardiac and Vascular
HCA Florida Largo Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic
HCA Florida Northside Hospital
- Cardiac and Vascular, Infectious Disease, Pulmonary and Thoracic
HCA Florida Trinity Hospital
- Infectious Disease
HCA Florida West Tampa
- Oncology